SCIENTIFIC PROGRAMME

Sunday, 20 March 2011

09:00-11:00	Session 1: Modeling of normal tissue effects
	Normal tissue dose-effect models and dose distribution Markus Alber (DE) Improving normal tissue complication probability models: the need to include biological mechanisms Peter van Luijk (NL) NTCP models for the pelvis: inclusion of predisposing clinical features Tiziana Rancati (IT) Proffered paper: PREDICTIVE MODELS FOR DYSPHAGIA AFTER (CHEMO)RADIATION IN HEAD AND NECK CANCER: A MULTICENTER PROSPECTIVE COHORT STUDY M. Christianen (NL) Proffered paper:  A NOVEL DOSE-RESPONSE MODEL FOR XEROSTOMIA ALLOWING FOR REGIONAL VARIATIONS IN RADIO-SENSITIVITY OF THE PAROTID F. Buettner (UK) Proffered paper:  CT-APPEARANCE OF LUNG RADIATION INJURY AFTER STEREOTACTIC BODY RADIATION THERAPY: DIFFERENCES BETWEEN PATIENTS WITH AND WITHOUT PULMONARY EMPHYSEMA S. Masciullo (IT)
11:00-11:30	Coffee and networking break
11:30-13:00	Session 2: Integrated dosimetric tools for prediction of normal tissue effects
	Clinical-dosimetric predictive modelling of radio-induced toxicity: the rectum paradigm Riccardo Valdagni (IT) Radiotherapy for early breast cancer  John Yarnold (UK) Individualized radical thoracic radiotherapy based on normal tissue dose constraints Philippe Lambin (NL)
13:00-14:30	Lunch
14:30-16:30	Session 3: Scoring system on new dose limits
	Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an overview Søren Bentzen (USA) Radiation dose and volume effect and tolerance Lawrence Marks (USA) The assessment of the potential benefit of new radiation techniques using prospective standardized follow up programs Hans Langendijk (NL) Proffered paper: NORMAL TISSUE TOXICITIES OF STEREOTACTIC BODY RADIATION THERAPY FOR THORACIC MALIGNANCIES B. Emami (USA) Proffered paper: IN VIVO IMAGING OF ORAL MUCOSA MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY TO PREDICT THE MUCOSITIS SEVERITY A. Maslennikova (Russian Federation) Proffered paper:  WHAT IS THE THRESHOLD DOSE FOR PROCESSES THAT LEAD TO THE DEVELOPMENT OF RADIATION PNEUMONITIS? M. Söhn (Germany)
16:30-17:00	Coffee and networking break
17:00-18.30	Session 4: New radiation technologies and their influence on normal tissue response
	Evaluation of normal tissue response to particle irradiation from preclinical studies: Radiobiological effectiveness and dose distribution Rob Coppes (NL) Ultra-high dose-rate, pulse irradiation to reduce the complications of radiotherapy Vincent Favaudon (FR)  The potential benefit of protons in reducing radiation induced side effects Hans Langendijk (NL)
18.30-19:30	Poster session and reception

Monday, 21 March 2011

09:00-10:30	Session 5: Cardiac damage
	The Biology of radiation-induced cardiac damage Saske Hoving (NL) Epidemiology of radiotherapy induced cardiac damage Sarah Darby (UK) Clinical experience of cardiac effects induced by anti-cancer treatment Stéphane Ederhy (FR)
10:30-11:00	Coffee and networking break
11:00-13:00	Session 6: Mechanisms of late vascular damage and potential dangers of anti-angiogenic therapy combined with radiation
	Mechanisms of late vascular damage after radiotherapy Marion Scharpfenecker (NL) Pre-clinical evaluation of the side-effects triggered by combination of bevacizumab and radiotherapy Marie-Catherine Vozenin-Brotons (FR) Clinical evaluation of treatment with Bevacizumab and radiotherapy Lukas Stalpers (NL) Proffered paper: IRRADIATED-VOLUME DEPENDENT PULMONARY VASCULAR REMODELING DETERMINES INDUCTION OF EARLY LUNG FUNCTION LOSS G. Ghobadi (NL) Proffered paper: DOSE-EFFECT RELATIONS FOR PREDICTING ACUTE ESOPHAGITIS AFTER IMRT CONCURRENT CHEMORADIOTHERAPY OF NON SMALL CELL LUNG CANCER BASED ON DOSE-SURFACE DISTRIBUTIONS C. Chen (NL) Proffered paper:  INCREASED RISK OF GASTROINTESTINAL CANCER IN HODGKIN LYMPHOMA PATIENTS: A DUTCH LONG-TERM FOLLOW-UP STUDY A. van Eggermond (NL)
13:00-14:30	Lunch and poster viewing
14:30-16:00	Session 7: Head & Neck
	Growth factors and amelioration of oral mucositis Wolfgang Dörr (DE) Brain stem cell replacement as an approach to reducing cognitive impairment after radiotherapy Charles Limoli (USA) Side-effects of Head and Neck cancer treatment and potential strategies to reduce them Chris Nutting (UK)
16:00-16:30	Keynote lecture
	Targeting angiogenesis or vasculogenesis in cancer therapy: advantages and potential risks Martin Brown (USA)